Dietary shochu kasu alleviates fatty liver induced by orotic acid
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منابع مشابه
Dietary Adenine Alleviates Fatty Liver Induced by Orotic Acid
The effects of dietary adenine in fatty liver induced by orotic acid (OA) were studied. Rats were paired-fed 1% OA-supplemented diets with/or without 0.25% adenine or a diet without OA for 10 days. Serum lipid profiles were measured using enzyme assay kits. Lipids of liver tissues were extracted and liver lipid contents were determined. A peach of liver was prepared to determine the activities ...
متن کاملFatty Livers Induced by Orotic Acid
Rats fed a purified diet supplemented with erotic acid (1%) have gross alterations in their lipid metabolism that can be essentially nullified by further supplementation of the diet with adenine sulfate (0.25%), as described in the first paper of this series (1). Accompanying these changes are certain alterations in the metabolism of pyrimidine derivatives, which have been described in an earli...
متن کاملDietary Food Fortified with Orotic Acid and Liver Function
The effects of dietary food fortified with orotic acid (1.0%) on liver function were studied in rats. The rats fed with orotic acid promoted liver triglyceride content markedly, that was 5-fold higher than that of the control. The liver malondialdehyde (MDA) content increased by 10%, but the gluthation peroxidase (GSH-Px) activity decreased by 50%. The serum aspartate aminotransferase (AST) and...
متن کاملAn integrated reverse functional genomic and metabolic approach to understanding orotic acid-induced fatty liver.
In functional genomics, DNA microarrays for gene expression profiling are increasingly being used to provide insights into biological function or pathology. To better understand the significance of the multiple transcriptional changes across a time period, the temporal changes in phenotype must be described. Orotic acid-induced fatty liver disease was investigated at the transcriptional and met...
متن کاملBiochemical and Nutritional Studies on the Induction of Fatty Livers by Dietary Orotic Acid.
3Canellakis, E. S., Biochim. Biophys. Acta, 25, 217 (1957). 4Hecht, L. I., P. C. Zamecnik, M. L. Stephenson, and J. F. Scott, J. Biol. Chem., 233, 954 (1958). 6 Zachau, H. G., G. Acs, and F. Lipmann, these PROCEEDINGS, 44, 885 (1958). 6 Preiss, J., P. Berg, J. Ofengand, F. H. Bergman, and M. Dieckman, these PROCVEDINGS, 45, 319 (1959). 7Hecht, L. I., M. L. Stephenson, and P. C. Zamecnik, these ...
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ژورنال
عنوان ژورنال: Bangladesh Journal of Pharmacology
سال: 2010
ISSN: 1991-0088,1991-007X
DOI: 10.3329/bjp.v5i1.5921